CBD has shown “promising” results to reduce inflammation and cognitive decline associated with aging, according to a recent government-funded study.
Researchers at University of Lethbridge and McGill University investigated the effects of non-intoxicating cannabidiol on aging mice, testing to see how long-term administration of CBD would impact memory, motor control functions and coordination that are linked to key parts of the brain.
The study, funded by the Canadian Institutes of Health Research and published in the journal Frontiers in Aging Neuroscience, found that “CBD treatment has a positive impact on object memory processes mediated by the [perirhinal cortex] and spatial memory functions centered on the [hippocampus].”
CBD has shown “promising” results to reduce inflammation and cognitive decline associated with aging, according to a recent government-funded study.
Researchers at University of Lethbridge and McGill University investigated the effects of non-intoxicating cannabidiol on aging mice, testing to see how long-term administration of CBD would impact memory, motor control functions and coordination that are linked to key parts of the brain.
The study, funded by the Canadian Institutes of Health Research and published in the journal Frontiers in Aging Neuroscience, found that “CBD treatment has a positive impact on object memory processes mediated by the [perirhinal cortex] and spatial memory functions centered on the [hippocampus].”
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“Brain pathology results showed that the aged mice treated with CBD showed reduced inflammation” in certain regions of the brain, including the hippocampus, which plays a key role in memory and learning, the authors wrote. Past studies have found that inflammation of those regions is linked to age-related dementia and other cognitive conditions.
CBD has shown “promising” results to reduce inflammation and cognitive decline associated with aging, according to a recent government-funded study.
Researchers at University of Lethbridge and McGill University investigated the effects of non-intoxicating cannabidiol on aging mice, testing to see how long-term administration of CBD would impact memory, motor control functions and coordination that are linked to key parts of the brain.
The study, funded by the Canadian Institutes of Health Research and published in the journal Frontiers in Aging Neuroscience, found that “CBD treatment has a positive impact on object memory processes mediated by the [perirhinal cortex] and spatial memory functions centered on the [hippocampus].”
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“Brain pathology results showed that the aged mice treated with CBD showed reduced inflammation” in certain regions of the brain, including the hippocampus, which plays a key role in memory and learning, the authors wrote. Past studies have found that inflammation of those regions is linked to age-related dementia and other cognitive conditions.
“CBD reduces inflammatory response in the brain and improves cognitive decline associated with aging.”
For the study, the scientists used 19 mice—10 of which received cannabidiol and nine that were given a placebo daily over the course of seven months. Throughout the experiment, the mice were subjected to a series of behavioral tests, including a “novel object recognition” task to assess visual memory, a balance beam task to gauge motor control and “fear conditioning”
“The results indicated that aged mice treated with CBD showed improved performance on the [novel object recognition] and [spacial learning], suggesting that CBD treatment has a positive impact on object memory processes mediated by the [perirhinal cortex] and spatial memory functions,” the study says.
“The findings of this study show that CBD targets inflammatory responses in the brain and can improve cognitive decline associated with aging,” the authors said, adding that it’s “possible that the effects of CBD treatment can be enhanced if an extract with THC and terpenoids is used.”
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