The Business of Cannabis

How Cannabis Compounds May Help Create Weight-Loss Drugs

Jun 9, 2026 | National

It’s a cannabis paradox. The drug famously triggers the munchies, yet regular users have lower rates of obesity and type 2 diabetes.

New research in mice, published in The Journal of Physiology, points to a potential explanation: Cannabis compounds may help regulate metabolism by enhancing “cross talk” between fat cells and the pancreas.

While delta-9-tetrahydrocannabinol (THC) is often touted for medicinal benefits, this study suggests that other, nonpsychoactive compounds might drive the plant’s metabolic perks.

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